MyBioSource.com's GADD45GIP1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry. The GADD45GIP1 Antibody was generated using CRIF1, and GADD45GIP1 as the antigen and it reacts with Human.
Description
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.Goernemann J., Virology 303:69-78(2002).Chung H.K., J. Biol. Chem. 278:28079-28088(2003).The MGC Project Team, Genome Res. 14:2121-2127(2004)